ProteoSys AG innovation in functional proteomics
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Lectures and posters  
Publications 2007-2008

Langer R, Ott K, Specht K, Becker K, Lordick F, Burian M, Herrmann K, Schrattenholz A, Cahill MA, Schwaiger M, Hofler H, Wester H-J (2008)
Protein Expression Profiling in Esophageal Adenocarcinoma Patients Indicates Association of Heat-Shock Protein 27 Expression and Chemotherapy Response
Clin Cancer Res 14: 8279-8287 [pubmed]

Weyrich A, Tang X, Xu G, Schrattenholz A, Hunzinger C, Hennig W (2008)
Mammalian DNMTs in the male germ line DNA of Drosophila
Biochem Cell Biol 86: 380-385 [pubmed]

Neubauer H, Clare SE, Wozny W, Schwall GP, Poznanović S, Stegmann W, Vogel U, Sotlar K, Wallwiener D, Kurek R, Fehm T, Cahill MA (2008)
Breast cancer proteomics reveals correlation between estrogen receptor status and differential phosphorylation of PGRMC1
Breast Cancer Res 10: R85, Erratum in: Breast Cancer Res (2009)
11: 401 [pubmed]

Leist M, Bremer S, Brundin P, Hescheler J, Kirkeby A, Krause KH, Poerzgen P, Puceat M, Schmidt M, Schrattenholz A, Zak NB, Hentze H (2008)
The biological and ethical basis of the use of human embryonic stem cells for in vitro test systems or cell therapy
ALTEX 25: 163-90 [pubmed]

Schrattenholz A, Šoškić V (2008)
What does systems biology mean for drug development?
Curr Med Chem 15: 1520-1528 [pubmed]

Šoškić V, Klemm M, Proikas-Cezanne T, Schwall GP, Poznanović S, Stegmann W, Groebe K, Zengerling H, Schöpf R, Burnet M, Schrattenholz A (2008)
A Connection between the Mitochondrial Permeability Transition Pore, Autophagy, and Cerebral Amyloidogenesis
J Proteome Res 7: 2262-2269 [pubmed]

Bunk S, Susnea I, Rupp J, Summersgill JT, Maass M, Stegmann W, Schrattenholz A, Wendel A, Przybylski M, Hermann C (2008)
Immunoproteomic Identification and Serological Responses to Novel Chlamydia pneumoniae Antigens That Are Associated with Persistent C. pneumoniae Infections
J Immunol 180: 5490-5498 [pubmed]

Köllermann J, Schlomm T, Bang H, Schwall G, von Eichel-Streiber C, Simon R, Schostak M, Huland H, Berg W, Sauter G, Klocker H, Schrattenholz A (2008)
Expression and Prognostic Relevance of Annexin A3 in Prostate Cancer
Eur Urol 54: 1314-1323 [pubmed]

Soškić V, Groebe K, Schrattenholz A (2008)
Nonenzymatic posttranslational protein modifications in ageing
Exp Gerontol 43: 247-257 [pubmed]

Cahill MA (2007)
Progesterone receptor membrane component 1: An integrative review
J Steroid Biochem Mol Biol 105: 16-36 [pubmed]

Groebe K, Krause F, Kunstmann B, Unterluggauer H, Sastri C, Stegmann W, Wozny W, Schwall GP, Poznanović S, Dencher NA, Jansen-Dürr P, Osiewacz HD and Schrattenholz A (2007)
Differential proteomic profiling of mitochondrial preparations from Podospora anserina, rat and human reveals distinct patterns of age-related oxidative changes
Exp Gerontol 42: 887-898 [pubmed]

Cahill MA, Vogt JA, Servos J, Wozny W, Schwall GP, Groebe K, Schrattenholz A and Stegmann W (2007)
Metabolically stable isotope labeling prior to electrophoretic protein separation reveals differences in fractional synthesis rates between mitochondrial aldehyde dehydrogenase isoforms
J Chromatogr A 1161: 67-70 [pubmed]

Neubauer H, Fehm T, Schutz C, Speer R, Solomayer E, Schrattenholz A, Cahill MA, Kurek R (2007)
Proteomic expression profiling of breast cancer
Recent Results Cancer Res., 176, 89-120 [pubmed]

Schrattenholz A and Groebe K (2007)
What does it need to be a biomarker? Relationships between resolution, differential quantification and statistical validation of protein surrogate biomarkers
Electrophoresis 28: 1970-1979 [pubmed]

Reineke J, Tenzer S, Rupnik M, Hasselmayer O, Schrattenholz A, Schild H, von Eichel-Streiber C (2007)
Autocatalytic cleavage of Clostridium difficile toxin B
Nature, 446: 415-419 [pubmed]

Schrattenholz A, Klemm M (2007)
Neuronal cell culture from human embryonic stem cells as in vitro model for neuroprotection
ALTEX 24: 9-15 [pubmed]

Wozny W, Schroer K, Schwall GP, Poznanović S, Stegmann W, Dietz K, Rogatsch H, Schaefer G, Huebl H, Klocker H, Schrattenholz A, Cahill MA (2007)
Differential radioactive quantification of protein abundance ratios between benign and malignant prostate tissues: cancer association of annexin A3
Proteomics 7: 313-322 [pubmed]